There are various forms in which CBD is available, including edibles, tinctures, vape oils, and capsules. The various means of using make CBD a handy and versatile compound. You can cater to your supplement wellness goals and preferences, with CBD products.


Your selection of delivery method will discover the strength and distribution of CBD in your system. How you take CBD also has an impact on the bioavailability of a compound. The bioavailability of a substance is the percentage that is digested into the bloodstream after any other processing in the human body.

Intravenous administration is supposed to have a 100% bioavailability; further methods are related to this route to produce a ratio for the percentage bioavailability. While the bioavailability percentages differ between studies, there is a commonality between many. The following is an overview of the bioavailability of three of the most common ways of CBD consumption:  inhalation, oral, and sublingual.

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CBD can be inhaled reliably with a vaporizer pen in the form of a vape oil. Vaping CBD is a relaxing technique that has increased popularity in the past years.

When inhaled, the CBD enters the lungs and reaches through little air sacs called alveoli, which transfer oxygen and carbon dioxide within the lungs and the bloodstream.

CBD goes through the thin surfaces of the alveoli and straight into the bloodstream. Again, this process bypasses the first-pass metabolism and therefore can have a higher bioavailability than oral consumption.

The bioavailability of THC inhalation is listed to be as high as 56%. Therefore, inhalation can have a greater bioavailability of sublingual control as well.

However, this amount ranges considerably due to the dynamics of smoking. The size and spacing of puffs, take time, and volume of inhalation can considerably affect the level of bioavailability.

Inhaling vaporized CBD oil is a fast and effective method. Since the oxygen is entering the bloodstream quickly, the effects of CBD are immediately present.


Oral consumption of CBD can include products such as capsules, edibles, and oils. This technique is popular due to its comfort of use. Oral consumption is a familiar and quick method that is used for several supplements.

When CBD used orally, It moves through the digestive system and flows through the liver. The bioavailability of CBD is decreased during what is known as “first pass metabolism”. When used, CBD is metabolized by the liver and in other places such as the lungs, gastrointestinal tract, and blood. This lowers the volume of CBD that is present in the bloodstream.

The bioavailability of THC by oral consumption varies from 4-20%. Sufficient data is not available for the bioavailability of CBD, which is why researchers are excited about the wealth of CBD research that is currently being carried. As discussed previously, factors such as digestion and metabolism are responsible for the low bioavailability.

While oral consumption has a moderate bioavailability than another method, it has been determined to have longer lasting results.


Sublingual stated “under the tongue” consumption can be made with products such as concentrates, tinctures, sprays, and lozenges. You may see that several CBD oils recommend sublingual use preferably than oral consumption due to its effectiveness.

When CBD applied sublingually, a substance is ingested by the mucous membrane under the tongue. Capillaries in the connective muscle diluted the substance, which then enters the bloodstream. In this manner, the substance bypasses the first-pass metabolism.

This estimates for a higher bioavailability than oral consumption. There is enough data to support that sublingual administration has a higher bioavailability than oral consumption; however, there are no particular percentages available.

Additional Factors

All methods are influenced by the hydrophobic features of CBD oil. CBD oil does not immediately dissolve in water and, for that purpose, it diffuses out of the bloodstream and accumulates in fatty tissues. This decreases the number of active CBD in the system, therefore lower bioavailability. CBD dosage and strength will also change the bioavailability of a substance.You might be interested  to buy cbd oil online then don’t forget to read the pros and cons of cbd oil.

The Bioavailability turns everything we use, including food and other items. While a low bioavailability may seem depressing, it is actually the contrary. Different bioavailabilities give the consumer options. A lower volume of CBD can serve well for some while higher values work well for others. Varying strengths makes CBD available for a deep range of people.